Preheat oven to 400° Fahrenheit. Cover flat surface with 2 to 3 layers paper towels, then place wire cooling rack over paper towels.
Place 6 tortillas on large baking sheet, making sure tortillas don't overlap. With pastry brush (or paper towel), lightly brush neutral-flavored oil on both sides of each tortilla. If desired, lightly sprinkle salt on both sides of each tortilla.
Place baking sheet in preheated oven. Bake tortillas 5 minutes, then carefully remove baking sheet from oven. Flip each tortilla over, making sure not to overlap tortillas, then return baking sheet to oven. Bake another 5 to 6 minutes or until tortillas are crispy and lightly browned.
When desired color is achieved, carefully remove baking sheet from oven. Transfer tostadas to wire cooling rack and set aside to allow excess oil to drip onto paper towels. Set aside.
For the Quick Guacamole
Add avocado flesh, red onion, cilantro, lime juice, and salt to medium bowl. Mash ingredients together with fork until desired guacamole texture is achieved. Set aside.
For the Tuna
Add 3 cans tuna (drained) to large mixing bowl. If needed, use fork to flake tuna, then add green onions, lime juice, cilantro, hot sauce, salt, and pepper. Stir well to fully incorporate all ingredients. Set aside.
For the Chipotle Aioli
Add mayo, garlic powder, and chipotle powder to small mixing bowl. Whisk until ingredients are fully incorporated.
Slowly add water to bowl in ½ tablespoon increments, whisking well between each addition, until desired consistency is achieved. If aioli becomes too thin, add mayo as needed in small increments to thicken.
To Serve
Top each tostada with equally-sized scoops of guacamole, followed by equally-sized scoops of tuna. Drizzle chipotle aioli over top of each tostada, then serve immediately.
Recipe Notes
Starting your layers with guacamole will help ensure the tuna (and any other toppings you may use) don't fall off the tostada.
Tuna: Any variety of canned tuna will work fine here!
Leftover Guacamole: Transfer guacamole to an airtight container and squeeze lemon juice over. Seal lid on container and refrigerate up to 2 days. Drain lemon juice before consuming guac.
Leftover Tuna: Refrigerate in an airtight container up to 4 days.
Leftover Chipotle Aioli: Refrigerate in an airtight container up to 7 days.
Leftover Tostadas: Store in an airtight container at room temperature up to 3 days. Consume at room temperature, or reheat in oven or air fryer on low heat until warmed through.
Make it Egg Free: Use vegannaise instead of traditional mayo.